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Viagra (Sildenafil citrate), which millions of men take for erectile dysfunction (ED), reduces the effects of hormonal stress on the heart by half, according to a study published online in the journal Circulation. Viagra causes genital blood vessels to expand, which helps in maintaining an erection. Recent research also has pointed to its potential usefulness in treating pulmonary hypertension. Prior to the latest findings by a team of Johns Hopkins researchers, it was thought to have little effect on the heart. Viagra, or sildenafil, blunts the strengthened heart beat caused by chemically induced stress, according to study senior author and cardiologist David Kass, MD, a professor at the Johns Hopkins University School of Medicine and its Heart Institute. It thereby lessens both the excess amount of blood and the force used to pump it to the body. "Sildenafil effectively puts a 'brake' on chemical stimulation of the heart," says Kass. Prevents and Reverses Effects of High BP These findings are believed to be the first confirmation in humans that Viagra has a direct effect on the heart. In earlier research, Kass and his team observed a similar effect in mice; Sildenafil blocked the short-term effects of hormonal stress in the heart. Related studies by the group show that sildenafil also prevents and reverses the long-term effects of chronic high blood pressure on the heart. Sildenafil reversed the negative effects on heart muscle weakened by heart failure and enlargement -- a condition called hypertrophy -- in mouse experiments Kass and his team carried out earlier this year. They reported their results in the journal Nature Medicine. "But we had no firm evidence as to whether or how this therapy might work in the human heart," says Kass. "Our latest research provides firm evidence this drug does indeed have an important impact on the heart." Increased Heartbeat Was Slowed Thirty-five healthy men and women, with an average age of 30 and no previous signs of coronary artery disease, participated in the six-month Johns Hopkins study. Within a three-hour timeframe, each participant received two separate injections of dobutamine (5 micrograms per kilogram for five minutes), a synthetic, adrenaline-like chemical that increases heart rate and pumping strength. Between injections, study participants were assigned randomly to a group that was treated with sildenafil (100 milligrams taken orally) or to a group given a sugar pill placebo. All participants then were given the second dobutamine injection to see what effects sildenafil or placebo had on the heart. Measurements of heart function were made before and after each injection. These included blood pressure readings, electrocardiograms and echocardiograms. Blood samples confirmed relatively equal levels of sildenafil and other enzymes. Each dobutamine injection stimulated heart function, increasing heart rate and the force of each heartbeat used to pump blood throughout the body, results showed. "This stimulation is similar to the way the nervous system normally increases heart function when triggered by emotional or exercise stress, or in diseases such as heart failure," notes Kass. After the first injection of dobutamine, the force of heart contraction increased by 150 percent in both groups. In the placebo group, this increase repeated itself after the second injection. However, in the group treated with sildenafil, the increased heartbeat was slowed by 50 percent, resulting in a smaller increase in blood flow and blood pressure generated by the heart in response to chemical stimulation. Between injections, heart function was not altered in the sildenafil group, demonstrating the absence of adverse side effects on the resting human heart. Stops PDE5A Action "Knowing more about the effects of sildenafil on heart function will allow for safer evaluation of its use as a treatment for heart problems," says Kass. "Our results set the stage for further studies of sildenafil's immediate and long-term effects on the heart and its ability to modify other neurohormonal and stress stimuli, including adrenaline and hypertension," he adds. While the precise biological actions of sildenafil in the heart are not fully understood, the drug is known to work by stopping the action of an enzyme, called phosphodiesterase 5 (PDE5A), Kass explains. This enzyme is involved in the breakdown of a key molecule, cyclic GMP, which helps control stresses and limit overgrowth in the heart. PDE5A is also the biological pathway that sildenafil blocks in the penis to prevent the relaxation of blood vessels and thus maintain erections. Copyright 2005 Daily News Central penis enlargement pills natural penis enhancement and lengthening natural penis elargement technique penis girth enlagement cheap penis elargement elargement manhattan penis penis enhancement pills penis enargement before and after picture

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The first step toward understanding how the prostate affects your health is to learn what the prostate is and how it functions. It is surprising how little many men know about such an important part of their anatomy. The prostate is an important segment of the male reproductive system. It is a gland that is located in the lower abdominal cavity, just below the bladder, in front of the rectum and behind the pubic bone. It partially surrounds the urethra. The urethra is the channel that carries urine to the penis from the bladder and it runs right through the prostate. A healthy prostate is about the size of a walnut, weighs approximately 1 ounce and is shaped similar to a donut. There are "seminal vesicles" that are attached to the prostate. They produce a protein that mixes with prostatic fluid which forms semen. How this works is that tubes from the testicles carry sperm up to the prostate where sperm is mixed with the seminal vesicle and prostatic fluids. This fluid is ejaculated during orgasm through ejaculatory ducts that connect to the urethra. In addition,the prostate helps to control the flow of urine. Nearly every man will experience some type of prostate problem during his lifetime. Men who are over forty-five may experience an enlargement of the prostate. While this is not a problem in itself, it is uncomfortable and can be a forerunner to other more serious maladies which we will discuss further. The prostate actually continues to grow throughout life, but grows very slowly after the age of twenty-five. Enlargement of the prostate is part of the normal aging process due to hormonal changes and usually does not become a serious problem until a man reaches sixty years of age. SYMPTOMS OF PROSTATE PROBLEMS Enlargement of the prostate is called benign prostate hyper- trophy, or BPH. While this growth is usually considered a nuisance, if a man experiences problems with burning, or difficult urination at any time, the prudent course of action is consulting a urologist. Other symptoms may be: 1. A feeling of having to push out urine 2. A sensation that the bladder is not emptying 3. Increased urinating, especially at night 4. Intermittent starting and stopping of the urinary stream After a diagnosis of BPH, many men will just continue to live with the symptoms and subsequent discomfort. It is not a life threatening condition. There are treatments. In some cases surgery might be considered if the enlargement is significant. Ignoring BPH can be extremely dangerous and lead to other disease such as kidney infections or damage as the urine can back up into the kidneys because of the blockage of an enlarged prostate. There can also be an occurrence of bladder infections. There is a huge difference between BPH and prostate cancer. BPH is a normal part of aging. Prostate cancer is a condition where prostate cells grow exponentially and out of control. These cells create tumors that may spread to any part of the body. Numerous health organizations report that 1 in 6 men will experience prostate cancer. However, if the condition is diagnosed early, approximately 99.3% of them will survive. The key is early detection. vigrx enhancement medical penis enlargement herbal penis elargement pills penis enlargement pill product medical penis enlarement truth about penis enhancement pills penis enargement program vimax pill penile enlargement pills review

Impotence occurs when one is unable to achieve or maintain an erection sufficient for satisfactory sexual intercourse. Although it tends to be more common in those who are over 40 year old, impotence can affect men of any age. A major study of impotence worldwide showed that over half of all men between 40 and 70 have some degree of impotence. At least one in ten men cannot get an erection at all. This website is aimed at helping those of us who believe that our penile size is insufficient to satisfy a woman fully and completely. However, if we have symptoms of impotence or erectile dysfunction, we should seek treatment for these conditions as soon as we can from a doctor. This is because impotence, even if it is just to the extent that the man cannot maintain an erection for a sufficiently long time during sexual intercourse, can also prevent a couple from having a fulfilling sexual relationship. Often, men will avoid sexual situations due to their emotional pain associated with impotence, causing their partner to feel rejected or inadequate. This also shows the importance of communicating openly with your partner, whether you may have symptoms of impotence or believe you have an inadequate penile size. A possible cause of impotency is premature ejaculation. This is the inability to maintain an erection long enough for mutual satisfaction. Primary premature ejaculation is a learned behavior that begins when a male first become sexually active. Like any learned behavior, it can be unlearned. Secondary premature ejaculation occurs when, after years of normal ejaculation, the duration of intercourse grows progressively shorter. This form of premature ejaculation is due to physical causes, usually involving the penile arteries, veins, or both. Other possible causes of impotence include performance anxiety, which is usually caused by stress or anxiety, depression, organic impotence, which involves the penile arteries, veins, or both, diabetes, nerve problems, drug-induced impotence and hormone-induced impotence. Visit Penile Enlargement Blog For More Advice. vig rx penis pill penis enhancement excercises does penile enlargement work penis elargement surgery cost herbal penis enlarement easy enlargement free penile surgery way enargement forum free matter penis size natural penis enargement exercise penile enlargement pills review

Whether a therapeutic technique is the best prostate cancer treatment for a patient depends on various factors. In selecting the treatment, a patient and his doctor should take into consideration the patient's age and expected life span, the stage and grade of the cancer, possible side effects and other health problems that the patient might have. One of the best prostate cancer treatment techniques, particularly for older men and those who suffer from other serious illnesses, is the expectant management or watchful waiting method. Watchful waiting involves the close monitoring of the cancer through prostate specific antigen testing. It does not involve active treatments like surgery and radiation therapy and is recommended mostly to those who have no symptoms. It is also used when the cancer is contained within one area of the prostate gland and is expected to grow very slowly. Another option available to prostate cancer patients is surgery. This can be radical retropubic prostatectomy, radical perineal prostatectomy, laparoscopic radical prostatectomy (LRP) or transurethral resection of the prostate (TURP). In retropubic prostatectomy, the surgeon makes an incision in the lower abdomen to remove the prostate gland. Lymph nodes around the prostate might also be removed depending on whether the cancer has spread to these parts. In perineal prostatectomy, the incision is made in the perineum or the skin between anus and scrotum. This procedure is use less often because the lymph nodes cannot be removed and there is a high probability that the nerves will be affected. LRP, on the other hand, involves the use of several smaller incisions and specialized instruments. This highly complex procedure is known for its high precision and control. In the hands of experienced surgeons, it becomes an advantageous option compared with retropubic and perineal prostatectomy. TURP, meanwhile, makes use of an instrument called a resectoscope which is passed through the end of the penis into the urethra at the level of the prostate. The electricity that passes through the instrument cuts or vaporizes the issue in the prostate. TURP is done to relieve symptoms and is also used for benign prostatic hyperplasia. Radiation therapy is the method in which high-energy rays or particles are used to kill cancer cells. This, like surgical procedures, is another example of a highly developed method of dealing with cancer. Radiation therapy is classified into two main types, the external beam radiation therapy (ERBT) and brachytherapy. In treating localized prostate cancer, a procedure called crysosurgery is sometimes used. It involves the freezing of the tissues using very cold gases. Aside from cryosurgery, hormone therapy and chemotherapy are also options that prostate cancer patients can explore. Hormone therapy does not cure cancer but is primarily used to lower levels of male hormones in a patient's body. Chemotherapy, meanwhile, is a procedure more commonly used in cases when the cancer has spread beyond the prostate gland. Choosing the best prostate cancer treatment depends on a lot of factors. What is considered appropriate for one patient might not be good for another, that's why options should be discussed in detail with doctors before proceeding to the treatment stage. free natural penile enlargement vimax penis enlargement supplement pro solution pills review permanent penis enlarement penile enlargment pump free penis elargement pills safe penis enlarement free natural penile enlargment penile enlargement pills review

Personal relationships can be seriously compromised by a continuing sexual problem. Such sexual dysfunction can cause terrible distress and can disrupt or even spell the end of personal relationship, regardless of which partner has the problem. Sexual dysfunction may be caused through physical problems but anxiety will often aggravate the dilemma. Sexual relationships are never entirely simple but they are very important and a source of much happiness for those in long term relationships. Many things, both physical and psychological, can go wrong and can threaten the fibre of the relationship if not dealt with in a proper manner. It is important for people to have some knowledge of what can impact on failure to achieve satisfactory sexual fulfillment. Such things can be caused by physical problems on the part of either partner or may be psychosomatic. Whatever the case, the problem affects both partners as such a relationship involves intense emotions and other mental factors. Factors such as faulty expectations, poor communication of sexual needs, ignorance, and concern over ability to perform can affect sexual function and satisfaction. Male Sexual Dysfunction Male dysfunction is most commonly in the form of the inability to achieve an erection or the inability to maintain an erection sufficiently to allow normal intercourse. This condition is known as impotence and can cause great distress to the male, not only because it prevents satisfying sexual intercourse but also because many men think it indicates a lack of masculinity. Most men suffer episodes of impotence at some time and these episodes are almost always of a psychological origin. Very few are attributable to disease and those cases that are, are usually among older men. Psychogenic impotence happens quite often because of performance anxiety. However, the majority of women do not place a great deal of importance on the occasional episode of impotence and are usually sympathetic and understanding rather than critical of their partner. They do not normally see it as a deficiency in the man’s masculinity. Sometimes, organic impotence can be helped by drugs like Viagra. In fact, it was only when Viagra was introduced to the market, the true prevalence of erectile dysfunction was revealed. Premature ejaculation, as its name implies, is when the male orgasm happens too early, thus depriving both partners of sexual satisfaction. This can even happen before penetration and is normally due to excessive excitement. This is fairly common in inexperienced men but will settle down as they become more sexually skilled. There is also a condition called Priapism that is potentially dangerous to the man. It is a rare condition in which the erection does not subside after he reaches orgasm. It is important that he seek immediate treatment as the blood in the penis will usually clot after about four hours, forming damaging internal scar tissue. The condition is usually treated by draining the blood under anaesthesia. Priapism has been known to be caused by drug abuse. Another disorder of the penis is Peyronie’s disease of which the cause is unknown. This disorder is characterized by a thickening and rigidity of tissue, resulting in a bend in the penis on erection. This can interfere with normal intercourse by causing discomfort to both partners. It may also prevent sexual intercourse from happening at all. The condition is often helped by steroid injections but surgical removal of the thickened areas is usually needed. Female Sexual Dysfunction Due to unrealistic expectations, many men see women who fail to achieve orgasm as being frigid. However, this often occurs because of a lack of affectionate expression by the partner, or a lack of sexual understanding and skill. Of course, there are other causes such as fear of pregnancy, recent childbirth, dyspareunia (pain during intercourse), and some prescription drugs. Drugs prescribed to treat conditions such as depression, insomnia, or high blood pressure can prevent female orgasm. Approximately ten percent of women will never achieve orgasm and around half never experience orgasm during sexual intercourse due to insufficient foreplay. Men often see the lack of female orgasm as a criticism of their own masculinity. Additional Sexual Problems Dyspareunia is the medical terminology for painful sexual intercourse which may be of physical or psychological origin. For instance, a woman who has recently had an episiotomy repair following childbirth will suffer from dyspareunia if she engages in sexual intercourse too soon. It may also be caused by infections in the uterus or the vagina or from rare congenital defects in the vagina. Pain can also be psychological and can be experienced because of fear or anger. It can also be an instinctive tactic to avoid unwanted sex. There is also an extreme condition called vaginismus which is an involuntary rejection of sexual intercourse and is difficult to treat. Sexual Therapy Those who suffer from any of the conditions mentioned may benefit from a referral to a therapist who will discuss treatment and options. Therapy can help couples overcome their fears of communicating sexual needs and their fear of rejection by their partner by using behavior therapy such as sensate focusing. This is generally a set of exercises that teach the partners to enjoy general body sensuality without intercourse. These exercises encourage a couple to enjoy body contact and sexual versatility and can help to overcome shyness which is sometimes still felt after many years of being together. Sexual intercourse is far more than a way of reproduction and includes intense emotions of attraction, love, and desire. These emotions generally begin in adolescence. When a loving bond is formed between two partners, it is important to look after that bond in any way possible.